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SERINC5-Mediated Restriction of HIV-1 Infectivity Correlates with Resistance to Cholesterol Extraction but Not with Lipid Order of Viral Membrane

Serine incorporator 5 (SER5) is a protein that upon incorporation into virions inhibits HIV-1 infectivity by interfering with the ability of the Env glycoprotein to promote viral fusion. The mechanisms by which SER5 antagonizes HIV-1 fusion are not well understood. A recent study of SER5’s structure...

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Autors principals: Gokul Raghunath, Yen-Cheng Chen, Mariana Marin, Hui Wu, Gregory B. Melikyan
Format: Artigo
Idioma:Inglês
Publicat: MDPI AG 2022-07-01
Col·lecció:Viruses
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Accés en línia:https://www.mdpi.com/1999-4915/14/8/1636
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