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CAPS-1 promotes fusion competence of stationary dense-core vesicles in presynaptic terminals of mammalian neurons

Neuropeptides released from dense-core vesicles (DCVs) modulate neuronal activity, but the molecules driving DCV secretion in mammalian neurons are largely unknown. We studied the role of calcium-activator protein for secretion (CAPS) proteins in neuronal DCV secretion at single vesicle resolution....

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Principais autores: Margherita Farina, Rhea van de Bospoort, Enqi He, Claudia M Persoon, Jan RT van Weering, Jurjen H Broeke, Matthijs Verhage, Ruud F Toonen
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications Ltd 2015-02-01
coleção:eLife
Assuntos:
CAPS protein
exocytosis
neuron
dense-core vesicle
trafficking
Acesso em linha:https://elifesciences.org/articles/05438
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