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A novel method for the synthesis of nicotinonitrile and diazepin derivatives under microwave irradiation

Abstract Ethyl 2-aryl-3-dimethylamino-acrylates 2a,b were prepared via the reaction of ethyl arylacetate with N,N-dimethylformamidedimethylacetal (DMFDMA) under microwave irradiation. Reaction of 2a,b with malononitrile afforded the corresponding substituted malononitrile derivatives 4a,b, which und...

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Autore principale: Mariam A. Al-Sheikh
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer 2010-07-01
Serie:Journal of Saudi Chemical Society
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Accesso online:https://doi.org/10.1016/j.jscs.2010.07.002
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