Liposomal Formulations of L-Asparaginase Conjugated with Cationic Polymers for Enhanced Internalization into Cancer Cells

L-asparaginase (L-ASNase) is a vital enzymatic drug widely used for treating acute lymphoblastic leukemia (ALL) and certain lymphomas. However, its clinical application is often limited by a short plasma half-life, pronounced immunogenicity, and systemic toxicities. To address these challenges, we r...

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Autores principales:	Igor D. Zlotnikov, Alexander A. Ezhov, Alexander V. Borisov, Andrey V. Lukyanov, Denis A. Babkov, Elena V. Kudryashova
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	MDPI AG 2025-11-01
Colección:	Macromol
Materias:	L-asparaginase liposomes drug delivery leukemia cationic polymers prolonged release
Acceso en línea:	https://www.mdpi.com/2673-6209/5/4/54
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