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Chalcones as Promising Antitumor Agents by Targeting the p53 Pathway: An Overview and New Insights in Drug-Likeness

The p53 protein is one of the most important tumor suppressors that are frequently inactivated in cancer cells. This inactivation occurs either because the <i>TP53</i> gene is mutated or deleted, or due to the p53 protein inhibition by endogenous negative regulators, particularly murine double minut...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Joana Moreira, Joana Almeida, Lucília Saraiva, Honorina Cidade, Madalena Pinto
Hōputu: Artigo
Reo:Inglês
I whakaputaina: MDPI AG 2021-06-01
Rangatū:Molecules
Ngā marau:
Urunga tuihono:https://www.mdpi.com/1420-3049/26/12/3737
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