Meningitic Escherichia coli-Induced Interleukin-17A Facilitates Blood–Brain Barrier Disruption via Inhibiting Proteinase 3/Protease-Activated Receptor 2 Axis

Bacterial meningitis is a life-threatening infectious disease with high morbidity and mortality worldwide, among which meningitic Escherichia coli is a common Gram-negative pathogenic bacterium causing meningitis. It can penetrate the blood–brain barrier (BBB), invoke local inflammatory responses an...

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Detalhes bibliográficos

Principais autores:	Bojie Xu, Jiaqi Chen, Jiyang Fu, Ruicheng Yang, Bo Yang, Dong Huo, Chen Tan, Huanchun Chen, Xiangru Wang
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2022-02-01
Colecção:	Frontiers in Cellular Neuroscience
Assuntos:	IL-17A Escherichia coli meningitis blood-brain barrier permeability PRTN3 PAR-2
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fncel.2022.814867/full
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