The mechanism of anticancer activity of the new synthesized compound - 6,7-Methylenedioxy-4-(2,4-dimethoxyphenyl)quinolin −2(1H)-one(12e) in human ovarian cancer cell lines

Objective: Ovarian cancer is the most lethal of the gynecologic malignancies. Most women have advanced disease at diagnosis and require extensive debulking surgery and aggressive chemotherapy. Induction of apoptosis in cancer cells has been used as an important approach for cancer therapy. We examin...

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Hauptverfasser: Hsu-Chin Chan, Yun-Han Liao, Heng-Wei Chang, Chung-Hsien Liu
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2021-03-01
Schriftenreihe:Taiwanese Journal of Obstetrics & Gynecology
Schlagworte:
4-Phenylquinolin-2(1H)-one
Anticancer agent
Ovarian cancer
Apoptosis
Online Zugang:http://www.sciencedirect.com/science/article/pii/S1028455921000024
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