Real-Life Vancomycin Therapeutic Drug Monitoring in Coagulase-Negative Staphylococcal Bacteremia in Neonatal and Pediatric Intensive Care Unit: Are We Underestimating Augmented Renal Clearance?

Bloodstream infections (BSI) from coagulase-negative-staphylococci (CoNS) are among the most frequent healthcare-related infections. Their treatment involves the use of vancomycin, a molecule whose optimal pharmacokinetic/pharmacodynamic (PK/PD) target for efficacy and safety is an area-under-curve/...

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Hauptverfasser:	Claudia Sette, Marcello Mariani, Luca Grasselli, Alessio Mesini, Carolina Saffioti, Chiara Russo, Roberto Bandettini, Andrea Moscatelli, Luca A. Ramenghi, Elio Castagnola
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	MDPI AG 2023-10-01
Schriftenreihe:	Antibiotics
Schlagworte:	vancomycin PK/PD TDM augmented renal clearance
Online-Zugang:	https://www.mdpi.com/2079-6382/12/11/1566
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