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Two specific drugs, BMS-345541 and purvalanol A induce apoptosis of HTLV-1 infected cells through inhibition of the NF-kappaB and cell cycle pathways

<p>Abstract</p> <p>Human T-cell leukemia virus type-1 (HTLV-1) induces adult T-cell leukemia/lymphoma (ATL/L), a fatal lymphoproliferative disorder, and HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP), a chronic progressive disease of the central nervous system after a long perio...

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Bibliografiset tiedot
Päätekijät: Wu Weilin, Kehn-Hall Kyleen, Pedati Caitlin, Klase Zachary, Berro Reem, Yeh Wen-I, Agbottah Emmanuel, Kashanchi Fatah
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BMC 2008-06-01
Sarja:AIDS Research and Therapy
Linkit:http://www.aidsrestherapy.com/content/5/1/12
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