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Zika Virus sfRNA Plays an Essential Role in the Infection of Insects and Mammals

Similar to other flaviviruses, Zika virus (ZIKV) produces abundant subgenomic flavivirus RNA (sfRNA) derived from the 3’ untranslated region. The molecular mechanisms that determine the functions of sfRNA are currently not completely understood. Here, we created ZIKV mutants deficient in sfRNA produ...

Deskribapen osoa

Gorde:
Egile Nagusiak: Andrii Slonchak, Leon E. Hugo, Morgan Freney, Alberto A Amarilla, Sonja Hall-Mendelin, Kexin Yan, Francisco Torres, Yin Xiang Setoh, Nias Peng, Harman K Chaggar, Andrew Van Den Hurk, Ernst Wolvetang, Andreas Suhrbier, Gregor J. Devine, Alexander A Khromykh
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: MDPI AG 2020-07-01
Saila:Proceedings
Gaiak:
Zika virus
subgenomic flavivirus RNA
apoptosis
type I interferon
foetal brain infection
Sarrera elektronikoa:https://www.mdpi.com/2504-3900/50/1/112
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