Distinct mutations in importin-β family nucleocytoplasmic transport receptors transportin-SR and importin-13 affect specific cargo binding

Abstract Importin-(Imp)β family nucleocytoplasmic transport receptors (NTRs) are supposed to bind to their cargoes through interaction between a confined interface on an NTR and a nuclear localization or export signal (NLS/NES) on a cargo. Although consensus NLS/NES sequence motifs have been defined...

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Manylion Llyfryddiaeth

Prif Awduron:	Makoto Kimura, Kenichiro Imai, Yuriko Morinaka, Yoshiko Hosono-Sakuma, Paul Horton, Naoko Imamoto
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	Nature Portfolio 2021-08-01
Cyfres:	Scientific Reports
Mynediad Ar-lein:	https://doi.org/10.1038/s41598-021-94948-1
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