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SOX9 Protein in Pancreatic Cancer Regulates Multiple Cellular Networks in a Cell-Specific Manner

SOX9 is upregulated in the majority of pancreatic ductal adenocarcinoma cases. It is hypothesized that the increased expression of SOX9 is necessary for the formation and maintenance of tumor phenotypes in pancreatic cancer cells. In our research, we studied six pancreatic cancer cell lines, which d...

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Principais autores: Eugene Kopantzev, Liya Kondratyeva, Marina Kopantseva, Kirill Kashkin, Dmitry Gnatenko, Elizaveta Grigorieva, Irina Alekseenko, Dina Safina, Igor Chernov
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2022-06-01
coleção:Biomedicines
Assuntos:
pancreatic ductal adenocarcinoma
transcription factor
SOX9
differentiation markers
cell proliferation
apoptosis
Acesso em linha:https://www.mdpi.com/2227-9059/10/7/1466
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