Genomic amplifications identified by circulating tumor DNA analysis guide prognosis in metastatic castration-resistant prostate cancer

PurposeAnalysis of circulating tumor DNA (ctDNA) in patients with metastatic prostate cancer (mPC) provides an opportunity to identify and monitor genomic alterations during a patient’s treatment course. We evaluated whether the presence of specific gene amplifications (GAs) and plasma copy number (...

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Auteurs principaux:	Toros A. Dincman, Joseph A. Q. Karam, Antonio Giordano, Hong Li, Leylah M. Drusbosky, Theodore S. Gourdin, Philip H. Howe, Michael B. Lilly
Format:	Artigo
Langue:	Inglês
Publié:	Frontiers Media S.A. 2024-02-01
Collection:	Frontiers in Oncology
Sujets:	prostate cancer metastasis castration-resistant prostate cancer androgen receptor PIK3CA aneuploidy
Accès en ligne:	https://www.frontiersin.org/articles/10.3389/fonc.2023.1202277/full
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