Notch activation promotes endothelial quiescence by repressing MYC expression via miR-218

After angiogenesis-activated embryonic and early postnatal vascularization, endothelial cells (ECs) in most tissues enter a quiescent state necessary for proper tissue perfusion and EC functions. Notch signaling is essential for maintaining EC quiescence, but the mechanisms of action remain elusive....

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Podrobná bibliografie

Hlavní autoři:	Jia-Xing Sun, Guo-Rui Dou, Zi-Yan Yang, Liang Liang, Juan-Li Duan, Bai Ruan, Man-Hong Li, Tian-Fang Chang, Xin-Yuan Xu, Juan-Juan Chen, Yu-Sheng Wang, Xian-Chun Yan, Hua Han
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Elsevier 2021-09-01
Edice:	Molecular Therapy: Nucleic Acids
Témata:	miR-218 endothelial cells Notch MYC angiogenesis quiescence
On-line přístup:	http://www.sciencedirect.com/science/article/pii/S2162253121001918
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