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Distinct Role of TNFR1 and TNFR2 in Protective Immunity Against Orientia tsutsugamushi Infection in Mice

Infection with Orientia tsutsugamushi, an obligate intracellular bacterium, can cause mild or severe scrub typhus. Some patients develop acute lung injury, multi-organ failure, and fatal infection; however, little is known regarding key immune mediators that mediate infection control or disease path...

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Hlavní autoři: Yuejin Liang, James Fisher, Casey Gonzales, Brandon Trent, Galen Card, Jiaren Sun, Alexei V. Tumanov, Lynn Soong
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2022-04-01
Edice:Frontiers in Immunology
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On-line přístup:https://www.frontiersin.org/articles/10.3389/fimmu.2022.867924/full
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