Non-ischemic Heart Preservation via Hypothermic Cardioplegic Perfusion Induces Immunodepletion of Donor Hearts Resulting in Diminished Graft Infiltration Following Transplantation

Introduction: Many donor organs contain significant leukocyte reservoirs which upon transplantation activate recipient leukocytes to initiate acute rejection. We aimed to assess whether non-ischemic heart preservation via ex vivo perfusion promotes immunodepletion and alters the inflammatory status...

Täydet tiedot

Bibliografiset tiedot

Päätekijät:	William R. Critchley, John P. Stone, Qiuming Liao, Guangqi Qin, Ivar Risnes, Andrew Trafford, Helge Scott, Trygve Sjöberg, Stig Steen, James E. Fildes
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	Frontiers Media S.A. 2020-07-01
Sarja:	Frontiers in Immunology
Aiheet:	heart transplantation acute rejection heart preservation hypothermic cardioplegic ex vivo heart perfusion passenger leukocytes
Linkit:	https://www.frontiersin.org/article/10.3389/fimmu.2020.01621/full
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