mRNA delivery systems 2.0: Engineering extrahepatic delivery for non-vaccine therapeutics

Recent breakthroughs in mRNA therapeutics have transformed vaccine development, largely powered by lipid nanoparticle (LNP) based delivery systems. However, these systems exhibit a strong hepatic tropism, making them suboptimal for targeting extrahepatic organs such as the brain, lungs, pancreas, he...

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Bibliografiske detaljer

Principais autores:	Manoj Dalabehera, Arnab Ghosh, Satyajit Mohanty, Dinesh Kumar Chellappan, Shubham Chaudhari, Yogita Ale, Neelam Poonia, Rudra Narayan Subudhi, Manmeet Kaur Khanna, Hae Gyun Lim
Format:	Artigo
Sprog:	Inglês
Udgivet:	Elsevier 2025-12-01
Serier:	Materials Today Bio
Fag:	mRNA Lipid nanoparticle Exosomes Ligand-receptor targeting Extra hepatic delivery
Online adgang:	http://www.sciencedirect.com/science/article/pii/S259000642501155X
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