Charge-Based Inhibitors of Amylin Fibrillization and Toxicity
To test the hypothesis that electrostatic repulsion is an important force opposing amyloid fibril assembly, we designed peptides that substitute strings of positively or negatively charged residues into the sequence of the amyloidogenic hormone amylin, which contributes to type 2 diabetes pathology....
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , |
|---|---|
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Wiley
2015-01-01
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| Σειρά: | Journal of Diabetes Research |
| Διαθέσιμο Online: | http://dx.doi.org/10.1155/2015/946037 |
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