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Causal structure discovery identifies risk factors and early brain markers related to evolution of white matter hyperintensities

Our goal was to understand the complex relationship between age, sex, midlife risk factors, and early white matter changes measured by diffusion tensor imaging (DTI) and their role in the evolution of longitudinal white matter hyperintensities (WMH). We identified 1564 participants (1396 cognitively...

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Principais autores: Xinpeng Shen, Sheelakumari Raghavan, Scott A. Przybelski, Timothy G. Lesnick, Sisi Ma, Robert I. Reid, Jonathan Graff-Radford, Michelle M. Mielke, David S. Knopman, Ronald C. Petersen, Clifford R. Jack Jr., György J. Simon, Prashanthi Vemuri
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2022-01-01
Serier:NeuroImage: Clinical
Fag:
Diffusion MRI
White matter health
FLAIR
White matter hyperintensities
Causal discovery
Online adgang:http://www.sciencedirect.com/science/article/pii/S2213158222001425
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