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Nitric oxide induces cell death by regulating anti-apoptotic BCL-2 family members.

Nitric oxide (NO) activates the intrinsic apoptotic pathway to induce cell death. However, the mechanism by which this pathway is activated in cells exposed to NO is not known. Here we report that BAX and BAK are activated by NO and that cytochrome c is released from the mitochondria. Cells deficien...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Colleen M Snyder, Emelyn H Shroff, Jing Liu, Navdeep S Chandel
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Public Library of Science (PLoS) 2009-09-01
Σειρά:PLoS ONE
Διαθέσιμο Online:http://europepmc.org/articles/PMC2741604?pdf=render
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