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Antiplasmodial Cyclodecapeptides from Tyrothricin Share a Target with Chloroquine

Previous research found that the six major cyclodecapeptides from the tyrothricin complex, produced by <i>Brevibacillus parabrevis</i>, showed potent activity against chloroquine sensitive (CQS) <i>Plasmodium falciparum</i>. The identity of the aromatic residues in the aromatic dipeptide unit in cyc...

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Principais autores: Adrienne N.-N. Leussa, Marina Rautenbach
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2022-06-01
Serier:Antibiotics
Fag:
antimicrobial peptides
cyclic peptides
tyrocidine
tyrothricin
antimalarial activity
malaria
Online adgang:https://www.mdpi.com/2079-6382/11/6/801
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