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Modulating cholesteryl ester transfer protein activity maintains efficient pre-β-HDL formation and increases reverse cholesterol transport[S]

The mechanism by which cholesteryl ester transfer protein (CETP) activity affects HDL metabolism was investigated using agents that selectively target CETP (dalcetrapib, torcetrapib, anacetrapib). In contrast with torcetrapib and anacetrapib, dalcetrapib requires cysteine 13 to decrease CETP activit...

Whakaahuatanga katoa

I tiakina i:
Ngā kaituhi matua: Eric J. Niesor, Christine Magg, Naoto Ogawa, Hiroshi Okamoto, Elisabeth von der Mark, Hugues Matile, Georg Schmid, Roger G. Clerc, Evelyne Chaput, Denise Blum-Kaelin, Walter Huber, Ralf Thoma, Philippe Pflieger, Makoto Kakutani, Daisuke Takahashi, Gregor Dernick, Cyrille Maugeais
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Elsevier 2010-12-01
Rangatū:Journal of Lipid Research
Ngā marau:
dalcetrapib
torcetrapib
anacetrapib
high density lipoprotein-functionality
apolipoproteins
bile acids and salts/metabolism
Urunga tuihono:http://www.sciencedirect.com/science/article/pii/S0022227520313559
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