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Clinical Significance of Elevated Levels of Soluble‐Form Immune Checkpoint Molecules in Patients With Aggressive Adult T‐Cell Leukemia‐Lymphoma

ABSTRACT Background Immune checkpoint (IC) pathways, including programmed death protein 1 (PD‐1), its ligand PD‐L1, and CTLA‐4, mediate negative regulatory signals in immune responses. Recent studies in autoimmune diseases and malignancies reported that the presence of the soluble form of these ICs...

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Bibliografske podrobnosti
Principais autores: Shigeo Fuji, Junya Makiyama, Kuniko Takano, Ilseung Choi, Takeo Suzuki, Chihiro Suminaka, Mao Kuroishi, Yosuke Iwasaki, Hidenori Kasahara, Yuma Tada, Yasuhiro Shingai, Sayako Yuda, Takafumi Yokota, Jun Ishikawa
Format: Artigo
Jezik:Inglês
Izdano: Wiley 2025-08-01
Serija:eJHaem
Teme:
Online dostop:https://doi.org/10.1002/jha2.70046
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