Methylglyoxal-Derived Advanced Glycation Endproducts Accumulate in Multiple Sclerosis Lesions

Multiple sclerosis (MS) is a demyelinating autoimmune disease in which innate and adaptive immune cells infiltrate the central nervous system (CNS) and damage the myelin sheaths surrounding the axons. Upon activation, infiltrated macrophages, CNS-resident microglia, and astrocytes switch their metab...

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Bibliografiske detaljer

Principais autores:	Suzan Wetzels, Tim Vanmierlo, Jean L. J. M. Scheijen, Jack van Horssen, Sandra Amor, Veerle Somers, Casper G. Schalkwijk, Jerome J. A. Hendriks, Kristiaan Wouters
Format:	Artigo
Sprog:	Inglês
Udgivet:	Frontiers Media S.A. 2019-04-01
Serier:	Frontiers in Immunology
Fag:	multiple sclerosis neuroinflammation α-dicarbonyl advanced glycation endproducts astrocytes
Online adgang:	https://www.frontiersin.org/article/10.3389/fimmu.2019.00855/full
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