Clonal biases dictate availability of colonic cancer driver mutations for transformation
Abstract Aged normal tissues harbour cancer mutations predisposing to transformation. However, how different pro-oncogenic events in the human colon compare in frequency, behaviour and subsequent transformation risk remains unclear. Here, we analyse mutation hotspot regions in five colorectal cancer...
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| Principais autores: | , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Nature Portfolio
2026-04-01
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| Series: | Nature Communications |
| Acceso en liña: | https://doi.org/10.1038/s41467-026-71944-5 |
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