Transport engineering for improving the production and secretion of valuable alkaloids in Escherichia coli

Microorganisms can be metabolically engineered to produce specialized plant metabolites. However, these methods are limited by low productivity and intracellular accumulation of metabolites. We sought to use transport engineering for producing reticuline, an important intermediate in the alkaloid bi...

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Hlavní autoři:	Yasuyuki Yamada, Miya Urui, Hidehiro Oki, Kai Inoue, Haruyuki Matsui, Yoshito Ikeda, Akira Nakagawa, Fumihiko Sato, Hiromichi Minami, Nobukazu Shitan
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Elsevier 2021-12-01
Edice:	Metabolic Engineering Communications
Témata:	Alkaloids Metabolic engineering Transport engineering E. coli Reticuline AtDTX1
On-line přístup:	http://www.sciencedirect.com/science/article/pii/S2214030121000249
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