Investigating proteogenomic divergence in patient-derived xenograft models of ovarian cancer

Abstract Within ovarian cancer research, patient-derived xenograft (PDX) models recapitulate histologic features and genomic aberrations found in original tumors. However, conflicting data from published studies have demonstrated significant transcriptional differences between PDXs and original tumo...

Täydet tiedot

Bibliografiset tiedot

Päätekijät:	Jesenia M. Perez, Jolene M. Duda, Joohyun Ryu, Mihir Shetty, Subina Mehta, Pratik D. Jagtap, Andrew C. Nelson, Boris Winterhoff, Timothy J. Griffin, Timothy K. Starr, Stefani N. Thomas
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	Nature Portfolio 2025-01-01
Sarja:	Scientific Reports
Aiheet:	Patient-derived xenograft models (PDX) Ovarian cancer Proteogenomics Mass spectrometry Proteomics
Linkit:	https://doi.org/10.1038/s41598-024-84874-3
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