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A non-linear partial least squares based on monotonic inner relation

A novel regression model, monotonic inner relation-based non-linear partial least squares (MIR-PLS), is proposed to address complex issues like limited observations, multicollinearity, and nonlinearity in Chinese Medicine (CM) dose-effect relationship experimental data. MIR-PLS uses a piecewise mapp...

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Autors principals: Xuepeng Zheng, Bin Nie, Jianqiang Du, Yi Rao, Huan Li, Jiandong Chen, Yuwen Du, Yuchao Zhang, Haike Jin
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2024-05-01
Col·lecció:Frontiers in Physiology
Matèries:
Chinese medicine
drug dose-effect relationship
partial least squares
non-linear modeling
monotonic cubic splines
Accés en línia:https://www.frontiersin.org/articles/10.3389/fphys.2024.1369165/full
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