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Exchange of a Single Amino Acid Residue in the HybG Chaperone Allows Maturation of All H2-Activating [NiFe]-Hydrogenases in Escherichia coli

The biosynthesis of the NiFe(CN)2CO organometallic cofactor of [NiFe]-hydrogenase (Hyd) involves several discreet steps, including the synthesis of the Fe(CN)2CO group on a HypD-HypC scaffold complex. HypC has an additional function in transferring the Fe(CN)2CO group to the apo-precursor of the Hyd...

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Autori principali: Alexander Haase, R. Gary Sawers
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2022-03-01
Serie:Frontiers in Microbiology
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Accesso online:https://www.frontiersin.org/articles/10.3389/fmicb.2022.872581/full
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