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Pathological insights from amyotrophic lateral sclerosis animal models: comparisons, limitations, and challenges

Abstract In order to dissect amyotrophic lateral sclerosis (ALS), a multigenic, multifactorial, and progressive neurodegenerative disease with heterogeneous clinical presentations, researchers have generated numerous animal models to mimic the genetic defects. Concurrent and comparative analysis of...

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Bibliographic Details
Main Authors: Longhong Zhu, Shihua Li, Xiao-Jiang Li, Peng Yin
Format: Artigo
Language:Inglês
Published: BMC 2023-09-01
Series:Translational Neurodegeneration
Subjects:
Online Access:https://doi.org/10.1186/s40035-023-00377-7
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