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Circulating microRNA Biomarkers of Thiazide Response in Hypertension

Background Thiazide diuretics are the second most frequently prescribed class of antihypertensives, but up to 50% of patients with hypertension have minimal antihypertensive response to thiazides. We explored circulating microRNAs (miRNAs) in search of predictive biomarkers of thiazide response. Met...

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Principais autores: Lakshmi Manasa S. Chekka, Marwa Tantawy, Taimour Langaee, Danxin Wang, Rolf Renne, Arlene B. Chapman, John G. Gums, Eric Boerwinkle, Rhonda M. Cooper‐DeHoff, Julie A. Johnson
Format: Artigo
Sprog:Inglês
Udgivet: Wiley 2024-02-01
Serier:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Fag:
antihypertensive response
biomarkers
blood pressure response
chlorthalidone
circulating microRNA
hydrochlorothiazide
Online adgang:https://www.ahajournals.org/doi/10.1161/JAHA.123.032433
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