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Adenylyl cyclase 1 as a major isoform to generate cAMP signaling for apoA-1-mediated cholesterol efflux pathway

HDL apoA-1-mediated cholesterol efflux pathway requires multiple cellular proteins and signal transduction processes, including adenylyl cyclase (AC)/cAMP signaling. Due to the existence of multiple transmembrane AC isoforms, it was not known how many AC isoforms are expressed and which ones are ess...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Wanze Tang, Weilie Ma, Hang Ding, Margarita Lin, Le Xiang, Guorong Lin, Zhizhen Zhang
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2018-04-01
Schriftenreihe:Journal of Lipid Research
Schlagworte:
macrophage
vesicle
lipid complex
filipin • cholesterol indicator
Online-Zugang:http://www.sciencedirect.com/science/article/pii/S0022227520339158
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