Retrospective study on <italic>MGMT</italic> methylation status and its clinical significance in gliomas

Background and purpose: Glioma is a common malignant tumor of central nervous system with poor prognosis. Postoperative concurrent chemoradiotherapy with temozolomide (TMZ) is the main treatment for glioma. The methylation status of the O6-methylguanine-DNA methyltransferase (MGMT) promoter can pred...

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Auteurs principaux:	Lin JIANG, Qiying LIU, Liqing JIA, Jing ZHANG, Heng CHANG, Tian XUE, Min REN, Qianming BAI, Xiaoli ZHU, Xiaoyan ZHOU
Format:	Artigo
Langue:	Inglês
Publié:	Editorial Office of China Oncology 2023-08-01
Collection:	Zhongguo aizheng zazhi
Sujets:	Glioma O6 methylguanine DNA methyltransferase Double/triple gene conjoint analysis Prognosis Temozolomide
Accès en ligne:	http://www.china-oncology.com/thesisDetails#10.19401/j.cnki.1007-3639.2023.08.003
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