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Inhibition of NLRP3 Inflammasome Activation and Pyroptosis in Macrophages by Taraxasterol Is Associated With Its Regulation on mTOR Signaling

Taraxasterol (TAS) is an active ingredient of Dandelion (Taraxacum mongolicum Hand. -Mazz.), a medicinal plant that has long been used in China for treatment of inflammatory disorders. But the underlying mechanism for its therapeutic effects on inflammatory disorders is not completely clear. Inflamm...

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Autors principals: Fan Yang, Xun-jia Ye, Ming-ye Chen, Hong-chun Li, Yao-feng Wang, Mei-yan Zhong, Chun-su Zhong, Bo Zeng, Li-hui Xu, Xian-hui He, Dong-yun Ouyang
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2021-02-01
Col·lecció:Frontiers in Immunology
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Accés en línia:https://www.frontiersin.org/articles/10.3389/fimmu.2021.632606/full
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