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Current Approaches and Techniques in Physiologically Based Pharmacokinetic (PBPK) Modelling of Nanomaterials

There have been efforts to develop physiologically based pharmacokinetic (PBPK) models for nanomaterials (NMs). Since NMs have quite different kinetic behaviors, the applicability of the approaches and techniques that are utilized in current PBPK models for NMs is warranted. Most PBPK models simulat...

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Principais autores: Wells Utembe, Harvey Clewell, Natasha Sanabria, Philip Doganis, Mary Gulumian
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2020-06-01
Serier:Nanomaterials
Fag:
nanomaterial
PBPK
absorption
distribution
metabolism
elimination
Online adgang:https://www.mdpi.com/2079-4991/10/7/1267
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