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Integrating single-cell and bulk transcriptomes identifies B cell features associated with neoadjuvant chemoradiotherapy sensitivity in rectal cancer

Abstract Neoadjuvant chemoradiotherapy (nCRT) is the main treatment for Locally Advanced Rectal Cancer (LARC). The response to nCRT varies from a complete response to no response. The impact of the B cells in this process is poorly understood. This study aimed to characterize the B cells types assoc...

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Bibliografski detalji
Glavni autori: Huang Xia, Yu Lin, Zeyuan Li, Lijing Zeng, Qiwei Yao, Benhua Xu, Rong Zheng
Format: Artigo
Jezik:Inglês
Izdano: Nature Portfolio 2026-01-01
Serija:Scientific Reports
Teme:
Online pristup:https://doi.org/10.1038/s41598-025-31068-0
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