Integrated proteomics and metabolomics analyses reveal new insights into the antitumor effects of valproic acid plus simvastatin combination in a prostate cancer xenograft model associated with downmodulation of YAP/TAZ signaling

Abstract Background Despite advancements in therapeutic approaches, including taxane-based chemotherapy and androgen receptor-targeting agents, metastatic castration-resistant prostate cancer (mCRPC) remains an incurable tumor, highlighting the need for novel strategies that can target the complexit...

Celý popis

Podrobná bibliografie

Hlavní autoři:	Federica Iannelli, Rita Lombardi, Susan Costantini, Maria Serena Roca, Laura Addi, Francesca Bruzzese, Elena Di Gennaro, Alfredo Budillon, Biagio Pucci
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	BMC 2024-11-01
Edice:	Cancer Cell International
Témata:	Drug repurposing Valproic acid Simvastatin Proteomics Metabolomics Prostate cancer
On-line přístup:	https://doi.org/10.1186/s12935-024-03573-1
Tagy:	Přidat tag Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!