CircGSAP regulates the cell cycle of pulmonary microvascular endothelial cells via the miR-942-5p sponge in pulmonary hypertension

Background We recently demonstrated that circGSAP was diminished in lung tissues from patients with pulmonary arterial hypertension and in hypoxia-induced pulmonary microvascular endothelial cells (PMECs). However, the underlying role of circGSAP in PMECs remains unknown. The study aimed to investig...

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Auteurs principaux:	Yuanyuan Sun, Wenhui Wu, Qinhua Zhao, Rong Jiang, Jinling Li, Lan Wang, Shijin Xia, Mingjie Liu, Sugang Gong, Jinming Liu, Ping Yuan
Format:	Artigo
Langue:	Inglês
Publié:	Frontiers Media S.A. 2022-08-01
Collection:	Frontiers in Cell and Developmental Biology
Sujets:	pulmonary hypertension second to chronic obstructive pulmonary disease pulmonary microvascular endothelial cells circGSAP miR-942-5p SMAD4
Accès en ligne:	https://www.frontiersin.org/articles/10.3389/fcell.2022.967708/full
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