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Analysis of Genomic DNA Methylation Levels in Human Placenta using Liquid Chromatography-Electrospray Ionization Tandem Mass Spectrometry

Background: DNA-methylation is a common epigenetic tool which plays a crucial role in gene regulation and is essential for cell differentiation and embryonic development. The placenta is an important organ where gene activity can be regulated by epigenetic DNA modifications, including DNA methylatio...

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Principais autores: Sulistyo Emantoko Dwi Putra, Corinna Neuber, Christoph Reichetzeder, Berthold Hocher, Burkhard Kleuser
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Physiol Biochem Press GmbH & Co KG 2014-03-01
coleção:Cellular Physiology and Biochemistry
Assuntos:
Pregnancy
Placenta
Methylation
Global
LC-MS/MS
Fetal programming
Clinical
Acesso em linha:http://www.karger.com/Article/FullText/358666
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