Transcriptomic signatures in brain and blood related to cognitive and psychiatric phenotypes of Prader–Willi syndrome

Abstract This study defined gene expression changes across different cell types in prefrontal cortex (PFC) of donors with Prader-Willi syndrome (PWS) compared to controls and examined relationships between these changes in blood and PWS symptoms. 8,338 long non-coding RNAs and 17,079 protein-coding...

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Principais autores:	Shokouh Shahrokhi, Emma K. Baker, Michael See, Mirana Ramialison, Dinusha Gamage, Fernando J. Rossello, Helen Heussler, Michael Duhig, Robert D. Nicholls, Anthony J. Hannan, Melissa C. Southey, Olivia Veatch, Waheeda Hossain, Minh Bui, David J. Amor, Merlin G. Butler, David E. Godler
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	Nature Portfolio 2025-12-01
סדרה:	Scientific Reports
נושאים:	RPS18 Prader-Willi syndrome Behavioral issues Intellectual functioning Brain transcriptomics
גישה מקוונת:	https://doi.org/10.1038/s41598-025-33041-3
תגים:	הוספת תג אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!