Comparing therapeutic modulators of the SOD1 G93A Amyotrophic Lateral Sclerosis mouse pathophysiology

IntroductionAmyotrophic Lateral Sclerosis (ALS) is a paralyzing, multifactorial neurodegenerative disease with limited therapeutics and no known cure. The study goal was to determine which pathophysiological treatment targets appear most beneficial.MethodsA big data approach was used to analyze high...

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Principais autores:	Albert J. B. Lee, Tyler E. Kittel, Renaid B. Kim, Thao-Nguyen Bach, Tian Zhang, Cassie S. Mitchell
Formato:	Artigo
Idioma:	Inglês
Publicado:	Frontiers Media S.A. 2023-01-01
Series:	Frontiers in Neuroscience
Assuntos:	Amyotrophic Lateral Sclerosis (ALS) motoneuron disease neuromuscular pharmacology mouse model SOD1 G93A mouse
Acceso en liña:	https://www.frontiersin.org/articles/10.3389/fnins.2022.1111763/full
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