Cerebrospinal fluid p-tau231 as an early indicator of emerging pathology in Alzheimer's disease

Summary: Background: Phosphorylated tau (p-tau) epitopes in cerebrospinal fluid (CSF) are accurate biomarkers for a pathological and clinical diagnosis of Alzheimer's disease (AD) and are seen to be increased in preclinical stage of the disease. However, it is unknown if these increases transpire e...

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Detalhes bibliográficos

Principais autores:	Nicholas J. Ashton, Andréa L. Benedet, Tharick A. Pascoal, Thomas K. Karikari, Juan Lantero-Rodriguez, Wagner S. Brum, Sulantha Mathotaarachchi, Joseph Therriault, Melissa Savard, Mira Chamoun, Erik Stoops, Cindy Francois, Eugeen Vanmechelen, Serge Gauthier, Eduardo R. Zimmer, Henrik Zetterberg, Kaj Blennow, Pedro Rosa-Neto
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2022-02-01
Colecção:	EBioMedicine
Assuntos:	Cerebrospinal fluid Phosphorylated tau Alzheimer's disease Preclinical Amyloid Positron emission tomography
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2352396422000202
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