Effect of miR-21 in mesenchymal stem cells-derived extracellular vesicles behavior

Abstract Background A challenging new branch of research related to aging-associated diseases is the identification of miRNAs capable of modulating the senescence-associated secretory phenotype (SASP) which characterizes senescent cells and contributes to driving inflammation. Methods Mesenchymal st...

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Principais autores:	Miriam Morente-López, Rocio Mato-Basalo, Sergio Lucio-Gallego, Concha Gil, Mónica Carrera, Juan A. Fafián-Labora, Jesús Mateos, María C. Arufe
Formato:	Artigo
Idioma:	Inglês
Publicado:	BMC 2023-12-01
Series:	Stem Cell Research & Therapy
Assuntos:	Mesenchymal stem cells (MSC) Extracellular vesicles (EV) miR-21-5p (miR-21) Syndecan-1 (SDC1) Senescence-associated secretory phenotype (SASP) Inflammaging
Acceso en liña:	https://doi.org/10.1186/s13287-023-03613-z
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