Transcriptomes of Injured Lamprey Axon Tips: Single-Cell RNA-Seq Suggests Differential Involvement of MAPK Signaling Pathways in Axon Retraction and Regeneration after Spinal Cord Injury

Axotomy in the CNS activates retrograde signals that can trigger regeneration or cell death. Whether these outcomes use different injury signals is not known. Local protein synthesis in axon tips plays an important role in axon retraction and regeneration. Microarray and RNA-seq studies on cultured...

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Автори:	Li-Qing Jin, Yan Zhou, Yue-Sheng Li, Guixin Zhang, Jianli Hu, Michael E. Selzer
Формат:	Artigo
Мова:	Inglês
Опубліковано:	MDPI AG 2022-07-01
Серія:	Cells
Предмети:	spinal cord injury single cell RNA-seq axon regeneration MAPK pathway circadian rhythm local protein synthesis
Онлайн доступ:	https://www.mdpi.com/2073-4409/11/15/2320
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