Intestinal-epithelial LSD1 controls goblet cell maturation and effector responses required for gut immunity to bacterial and helminth infection.

Infectious and inflammatory diseases in the intestine remain a serious threat for patients world-wide. Reprogramming of the intestinal epithelium towards a protective effector state is important to manage inflammation and immunity and can be therapeutically targeted. The role of epigenetic regulator...

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Hlavní autoři:	Naveen Parmar, Kyle Burrows, Pia M Vornewald, Håvard T Lindholm, Rosalie T Zwiggelaar, Alberto Díez-Sánchez, Mara Martín-Alonso, Madeleine Fosslie, Bruce A Vallance, John Arne Dahl, Colby Zaph, Menno J Oudhoff
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Public Library of Science (PLoS) 2021-03-01
Edice:	PLoS Pathogens
On-line přístup:	https://doi.org/10.1371/journal.ppat.1009476
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