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Native American ancestry and breast cancer risk in Colombian and Mexican women: ruling out potential confounding through ancestry-informative markers

Abstract Background Latin American and Hispanic women are less likely to develop breast cancer (BC) than women of European descent. Observational studies have found an inverse relationship between the individual proportion of Native American ancestry and BC risk. Here, we use ancestry-informative ma...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Linda Zollner, Diana Torres, Ignacio Briceno, Michael Gilbert, Gabriela Torres-Mejía, Joe Dennis, Manjeet K. Bolla, Qin Wang, Ute Hamann, Justo Lorenzo Bermejo
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMC 2023-10-01
Schriftenreihe:Breast Cancer Research
Schlagworte:
Genetic admixture
Ancestry-informative markers
Causal inference
Instrumental variables
Mendelian randomization
Online-Zugang:https://doi.org/10.1186/s13058-023-01713-5
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