An experimental strategy unveiling exosomal microRNAs 486-5p, 181a-5p and 30d-5p from hypoxic tumour cells as circulating indicators of high-risk rectal cancer

Tumour hypoxia contributes to poor treatment outcome in locally advanced rectal cancer (LARC) and circulating extracellular vesicles (EVs) as potential biomarkers of tumour hypoxia and adverse prognosis have not been fully explored. We examined EV miRNAs from hypoxic colorectal cancer cell lines as...

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Detalhes bibliográficos

Principais autores:	Tonje Bjørnetrø, Kathrine Røe Redalen, Sebastian Meltzer, Nirujah Sivarajah Thusyanthan, Rampradeep Samiappan, Caroline Jegerschöld, Karianne Risberg Handeland, Anne Hansen Ree
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Wiley 2019-12-01
coleção:	Journal of Extracellular Vesicles
Assuntos:	colorectal cancer extracellular vesicles hypoxia mirna plasma rectal cancer exosomes
Acesso em linha:	http://dx.doi.org/10.1080/20013078.2019.1567219
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