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Gingipain R1 and Lipopolysaccharide From Porphyromonas gingivalis Have Major Effects on Blood Clot Morphology and Mechanics

Background:Porphyromonas gingivalis and its inflammagens are associated with a number of systemic diseases, such as cardiovascular disease and type 2 diabetes (T2DM). The proteases, gingipains, have also recently been identified in the brains of Alzheimer's disease patients and in the blood of Parki...

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Main Authors: J. Massimo Nunes, Tristan Fillis, Martin J. Page, Chantelle Venter, Ophélie Lancry, Douglas B. Kell, Ursula Windberger, Etheresia Pretorius
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Immunology
Subjects:
Gingipain R1
lipopolysaccharide
Porphyromonas gingivalis
thromboelastography
rheometry
confocal
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.01551/full
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