Non-redundant roles of the CCR1 and CCR2 chemokine axes in monocyte recruitment during lung metastasis

Monocytes and monocyte-derived macrophages facilitate cancer progression and metastasis. Inflammatory monocytes expressing CCR2 are actively recruited to metastatic lungs, where they promote tumor cell extravasation, metastatic outgrowth, and an immunosuppressive environment. The role of CCR1 in thi...

Celý popis

Podrobná bibliografie

Hlavní autoři:	Alessia G. Liner, Merel van Gogh, Marko Roblek, Matthias Heikenwalder, Lubor Borsig
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Elsevier 2025-01-01
Edice:	Neoplasia: An International Journal for Oncology Research
Témata:	lung metastasis monocyte recruitment macrophages CCR1 CCR2
On-line přístup:	http://www.sciencedirect.com/science/article/pii/S1476558624001301
Tagy:	Přidat tag Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!