Berberine and berberrubine promote the expression of CYP3A4 via enhancing the binding of nuclear receptor PXR
Abstract Background Berberine is currently co-administered with statins in clinical practice for hyperlipidemia management. This study aimed to investigate the effects of berberine and berberrubine on CYP3A4 expression and the regulatory mechanism. Methods Using rifampicin as a positive control grou...
Salvato in:
| Autori principali: | , , , |
|---|---|
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BMC
2025-11-01
|
| Serie: | BMC Pharmacology and Toxicology |
| Soggetti: | |
| Accesso online: | https://doi.org/10.1186/s40360-025-01026-7 |
| Tags: |
Nessun Tag, puoi essere il primo ad aggiungerne!!
|